2024

Adam S*, Maas SL*, Huchzermeier R, Rakateli L, Abschlag K, Hohl M, Liao L, Bartneck M, Teunissen M, Wouters K, Santovito D, Jankowski J, Biessen EAL, van der Vorst EPC. The calcium-sensing-receptor (CaSR) in adipocytes contributes to sex-differences in the susceptibility to high fat diet induced obesity and atherosclerosis. EBioMedicine. 2024 Sep;107:105293.

 

Döring Y*, Van der Vorst EP*, Yan Y*, Neideck C*, Blanchet X, Jansen Y, Kemmerich M, Bayasgalan S, Peters LJ, Hristov M, Bidzhekov K, Yin C, Zhang X, Leberzammer J, Li Y, Park I, Kral M, Nitz K, Parma L, Gencer S, Habenicht AJ, Faussner A, Teupser D, Monaco C, Holdt L, Megens RT, Atzler D, Santovito D, Von Hundelshausen P, Weber C. Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis. Nature Cardiovascular Research. 2024 Jan

 

Christ A*, Maas SL*, Jin H, Lu C, Legein B, Wijnands E, Temmerman L, Otten J, Isaacs A, Zenke M, Stoll M, Biessen EA*, Van der Vorst EP*. In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells. Free Radical and Medicine. 2024 Jan; 210:406-415

 

2023

Van der Vorst EP, Maas SL, Theodorou K, Peters LJ, Jin H, Rademakers T, Gijbels MJ, Rousch M, Jansen Y, Weber C, Lehrke M, Lebherz C, Yildiz D, Ludwig A, Bentzon JF, Biessen EA, Donners MM.

Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque haemorrhage and neovascularization in mice. Frontiers in Cardiovascular Medicine. 2023 Jan; 10:974918

 

2022

Gencer S, Döring Y, Jansen Y, Bayasgalan S, Yan Y, Bianchini M, Cimen I, Müller M, Peters LJ, Megens RT, Aslani M, Von Hundelshausen P, Duchence J, Lemnitzer P, Soehnlein O, Weber C, Van der Vorst EP. Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium. Basic Research in Cardiology. 2022 Jun; 117(1):30

 

Peters LJ, Baaten CC, Maas SL, Lu C, Nagy M, Jooss NJ, Bidzhekov K, Santovito D, Moreno-Andres D, Jankowski J, Biessen EA, Döring Y, Heemskerk JW, Weber C, Kuipers MJ, Van der Vorst EP. MicroRNA-26b attenuates platelet adhesion and aggregation in mice. Biomedicines. 2022 Apr; 10(5):983

 

2021

Sundararaman SS, Peters LJ, Nazir S, Bonnin Marquez A, Bouma JE, Bayasgalan S, Döring Y, Van der Vorst EP. PCSK9 imperceptibly affects chemokine receptor expression in vitro and in vivo.
International Journal Molecular Science. 2021 Dec; 22(23):13026

 

Van der Vorst EP*, Pepe MA*, Peters LJ, Haberbosch M, Jansen Y, Nauman R, Stathopoulos GT, Weber C, Bidzhekov K. Transcriptome signature of miRNA-16b KO mouse model suggests novel targets. BMC Genomic Data. 2021 Jun; 22(1):23

 

Sundararaman SS, Peters LJ, Jansen Y, Gencer S, Yan Y, Nazir S, Bonnin Marquez A, Kahles F, Lehrke M, Biessen EA, Jankowski J, Weber C, Döring Y, Van der Vorst EP. Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe-/- mice. Scientific Reports. 2021 May; 11(1):10409

 

Gencer S, Döring Y, Jansen Y, Bayasgalan S, Schengel O, Müller M, Peters LJ, Weber C, Van der Vorst EP. Adipocyte-specific ACKR3 regulates lipid levels in adipose tissue. Biomedicines. 2021 Apr; 9(4):394

 

2020

Döring Y, Jansen Y, Cimen I, Aslani M, Gencer S, Peters LJ, Duchene J, Weber C*, Van der Vorst EP*. B-cell specific CXCR4 protects against atherosclerosis development and increases plasma IgM levels. Circulation Research. 2020 Mar; 126(6): 787-788

 

Van der Vorst EP, Daissormont I, Aslani M, Seijkens T, Wijnands E, Lutgens E, Duchene J, Santovito D, Döring Y, Halvorsen B, Aukrust P, Weber C, Höpken UE, Biessen EA. Interruption of the CXCL13/CXCR5 chemokine axis enhances plasma IgM levels and attenuates atherosclerosis development. Thombosis & Heamostasis. 2020 Feb; 120(2): 344-347

 

2019

Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJ, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JW, Van der Vorst EP*, Döring Y*, Reinhardt C*. The microbiota promotes arterial thrombosis in low-density lipoprotein receptor-deficient mice. mBio. 2019 Oct; 10(5): e02298-19

 

Van der Vorst EP*, Döring Y*, Duchene J, Jansen Y, Gencer S, Bidzhekov K, Atzler D, Santovito D, Rader DJ, Saleheen D, Weber C. CXCL12 derived from endothelial cells promotes atherosclerosis to drive coronary artery disease. Circulation. 2019 Mar; 139(10): 1338-1340

 

Van der Vorst EP*, Mandl M*, Müller M, Neideck C, Jansen Y, Hristov M, Gencer S, Peters LJ, Meiler S, Feld M, Geiselhöringer AL, De Jong RJ, Ohnmacht C, Noels H, Soehnlein O, Drechsler M, Weber C, Döring Y. Hematopoietic ChemR23 (Chemerin Receptor 23) fuels atherosclerosis by sustaining an M1 macrophage-phenotype and guidance of plasmacytoid dendritic cells to murine lesions. Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Apr; 39(4): 685-693

 

Until 2018

Van der Vorst EP*, Theodorou K*, Gijbels MJ, Wolfs IM, Jeurissen M, Theelen TL, Sluimer JC, Wijnands E, Cleutjens JP, Li Y, Jansen Y, Weber C, Ludwig A, Bentzon JF, Bartsch JW, Biessen EA, Donners MM. Hematopoietic ADAM8 deficiency does not influence atherosclerotic plaque area or composition, despite its upregulation during plaque progression. Scientific Reports. 2017 Sep; 7(1)

 

Van der Vorst EP*, Rademakers T*, Daissormont IT*, Otten JJ, Theelen TL, Gijbels M, Anisimov A, Nurmi H, Lindeman JH, Schober A, Heeneman S, Alitalo K, Biessen EA. Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis. Scientific Reports. 2017 Mar; 7

 

Van der Vorst EP*, Zhao Z*, Rami M, Holdt LM, Teupser D, Steffens S#, Weber C#. Contrasting effects of myeloid and endothelial ADAM17 on atherosclerosis development. Thrombosis & Heamostasis. 2017 Feb; 117(3): 644-646

 

Van der Vorst EP*, Theodorou K*, Wu Y, Hoeksema MA, Goossens P, Bursill CA, Aliyev T, Huitema LF, Tas SW, Wolfs IM, Kuijpers MJ, Gijbels MJ, Schalkwijk CG, Koonen, Abdollahi-Roodsaz S, McDaniels K, Wang CC, Leitges M, Lawrence T, Plat J, Van Eck M, Rye KA, Touqui L, De Winther MP, Biessen EA, Donners MM. High Density Lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-κB/STAT1-IRF1 activation. Cell Metabolism. 2017 Jan; 25(1): 197-207

 

Van der Vorst EP, Wolfs IM, Jeurissen M, Keijbeck A, Wijnands E, Schurgers L, Weber S, Gijbels MJ, Dreymueller D, Hamers AA, Rose-John S, de Winther MP, Ludwig A, Saftig P, Biessen EA, Donners MM. Myeloid A Disintegrin and Metalloproteinase Domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.
American Journal of Pathology. 2015 Apr; 185(4): 1145-1155

 

Van der Vorst EP*, Vanags LZ*, Dunn LL, Prosser HC, Rye KA, Bursill CA. High-Density Lipoproteins Suppress Chemokine Expression and Proliferation in Human Vascular Smooth Muscle Cells.
FASEB Journal. 2013 Apr; 27(4): 1413-1425

 

*denotes shared authorship

Reviews (selection)