Overview of already optimized samples. Other samples are possible, but require small test.
| Species | Tissue / Cells | Sample type |
|---|---|---|
| Human | Cells | HAoSMCs |
| Human | Cells | HCAECs |
| Human | Cells | Platelets |
| Human | Cells | Periodontal ligament stem cells |
| Human | Cells | Dermal fibroblast |
| Human | Cells | EGI1 |
| Human | Cells | MDA-MB-453 |
| Human | Cells | MDA-MB-231 |
| Human | Cells | PSN-1 |
| Human | Cells | PANC-1 |
| Human | Cells | SKGT4 |
| Human | Cells | U-1242 |
| Human | Cells | SCaBER |
| Human | Cells | Mast cells |
| Human | Cells | T cells |
| Human | Cells | PBMCs |
| Human | Cells | HepG2 |
| Human | Cells | THP-1 |
| Human | Cells | Cementoblasts |
| Human | Tissue | Brain |
| Human | Tissue | Breast speroids |
| Human | Tissue | Heart |
| Human | Tissue | Liver |
| Species | Tissue / Cells | Sample type |
|---|---|---|
| Mouse | Cells | Platelets |
| Mouse | Cells | Bone marrow derived macrophages |
| Mouse | Cells | HL-1 |
| Mouse | Cells | mIMCD-3 |
| Mouse | Cells | Cardiomyocytes |
| Mouse | Cells | Microglia |
| Mouse | Tissue | Heart |
| Mouse | Tissue | Kidney |
| Mouse | Tissue | Aorta |
| Mouse | Tissue | Brain |
| Mouse | Tissue | Intestine |
| Mouse | Tissue | Liver |
| Mouse | Tissue | Adipose tissue |
| Mouse | Tissue | Tumour |
Overview of published manuscripts using our kinomics facility.
| Main author | Title | Journal | Year |
|---|---|---|---|
| Emiel van der Vorst (Aachen, DE) | The calcium-sensing-receptor (CaSR) in adipocytes contributes to sex-differences in the susceptibility to high fat diet induced obesity and atherosclerosis. | EBioMedicine | 2024 |
| Sarah-Lena Puhl (Munich, Würzburg, DE) | pr55 deficiency crucially alters cardiomyocyte homeostasis and counteracts angiotensin II induced maladaption in female mice. | British Journal of Pharmacology | 2024 |
| Edgar Dahl (Aachen, DE) | ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration | Molecular Oncology | 2024 |
| Sabine Neuss (Aachen, DE) | Identifying Differences in Molecular Characteristics Relevant for Remodeling of Periodontal Ligament Stem Cells from the Upper and Lower Jaw | International Journal of Molecular Sciences | 2024 |
| Sabine Steffens (Munich, DE) | Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner | Cardiovascular Research | 2024 |
| Emiel van der Vorst (Aachen, DE) | Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice | Frontiers in Cardiovascular Medicine | 2023 |
| Marijke Kuijpers (Maastricht, NL) | Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-Induced Coagulation: Additive Effects of Aspirin | Thrombosis & Haemostasis | 2022 |
| Throsten Kessler (Munich, DE) | Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation | Nature Cardiovascular Research | 2022 |
| Emiel van der Vorst (Aachen, DE) | MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice | Biomedicines | 2022 |
| Claudia Goettsch (Aachen, DE) | Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro | Frontiers in Cardiovascular Medicine | 2022 |
| Joachim Jankowski (Aachen, DE) | Prevention of vascular calcification by the endogenous chromogranin A-derived mediator that inhibits osteogenic transdifferentiation | Basic Research in Cardiology | 2021 |
| Marijke Kuijpers (Maastricht, NL) | Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function | eJHaem | 2021 |